2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-E70182
    Hyaluronidase 2 98%
    Hyaluronidase 2 (EC:3.2.1.35; HYAL2) is a hyaluronidase. Hyaluronidase 2 cleaves high-molecular-weight hyaluronan into intermediate, ~20 kDa, and tetrasaccharide fragments. Hyaluronidase 2 directly interacts with CD44 and ERM proteins, reduces CD44 hyaluronan binding capacity and ERM activation. Hyaluronidase 2 can be used for the research of gliomas, inflammatory bowel disease, congenital heart defects, heart failure.
    Hyaluronidase 2
  • HY-E70199
    Aminopeptidase N (rat) 9054-63-1 98%
    Aminopeptidase N (rat) (APN/CD13) is a Zn2+-dependent membrane-bound exopeptidase that preferentially degrades proteins and peptides with N-terminal neutral amino acids. Aminopeptidase N (rat) is inhibited by angiotensin IV and participates in the regulation of angiotensin IV half-life in the rat striatum.
    Aminopeptidase N (rat)
  • HY-E70252
    1-Pyrenebutanoyl-CoA 81923-89-9 98%
    1-Pyrenebutanoyl-CoA is a type of coenzyme A that can non-competitively inhibit (Ki = 2 μM) phosphorylating (ADP-stimulated) respiration in rat liver mitochondria, and competitively inhibit (Ki = 2.1 μM and 15 μM) carnitine palmitoyl-CoA transferase and octanoyl-CoA transferase.
    1-Pyrenebutanoyl-CoA
  • HY-E70292
    N-Acetylgalactosaminyltransferase 11 98%
    N-Acetylgalactosaminyltransferase 11 (GALNT11) is a glycosylation transferase capable of activating the Notch signal.
    N-Acetylgalactosaminyltransferase 11
  • HY-E70389
    Human Kallikrein
    Human Kallikrein is a serine protease that can be found in plasma and tissue. Human Kallikrein has the potential for the research of blood pressure, complement activation, and mediation and maintenance of inflammatory responses.
    Human Kallikrein
  • HY-E70390
    C1s Enzyme
    C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity.
    C1s Enzyme
  • HY-E70413
    Amino acid arylamidase, hog kidney 9012-21-9 98%
    Amino acid arylamidase, hog kidney is a metalloprotease that can hydrolyze proteins or peptides containing free α-amino or α-imino groups, playing a crucial role in amino acid metabolism and protein digestion. Its hydrolytic activity can be blocked by acetylation of the N-terminus. Amino acid arylamidase, hog kidney can be used in research on hepatic diseases, biliary diseases, and heart failure.
    Amino acid arylamidase, hog kidney
  • HY-E70542
    Bovine Factor V/Va 98%
    Bovine Factor V/Va can be purified from fresh bovine plasma and used as a source of V/Va in the prothrombinase complex.
    Bovine Factor V/Va
  • HY-E70559
    Prostaglandin D synthase 65802-85-9 98%
    Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type Prostaglandin D synthase (L-PGDS) is present in the atherosclerotic plaque of the human coronary artery and can be detectable in human serum.
    Prostaglandin D synthase
  • HY-E70782
    TIE2 R849W Recombinant Human Active Protein Kinase
    TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 R849W is the most common mutation implicated in an inherited form of vascular malformations. TIE2 R849W Recombinant Human Active Protein Kinase is a recombinant TIE2 R849W protein that can be used to study TIE2 R849W-related functions.
    TIE2 R849W Recombinant Human Active Protein Kinase
  • HY-E70783
    TIE2 Y1108F Recombinant Human Active Protein Kinase
    TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y1108F is the most mutation of TIE2. TIE2 Y1108F Recombinant Human Active Protein Kinase is a recombinant TIE2 Y1108F protein that can be used to study TIE2 Y1108F-related functions.
    TIE2 Y1108F Recombinant Human Active Protein Kinase
  • HY-E70784
    TIE2 Y897S Recombinant Human Active Protein Kinase
    TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y897S is the most mutation of TIE2. TIE2 Y897S Recombinant Human Active Protein Kinase is a recombinant TIE2 Y897S protein that can be used to study TIE2 Y897S-related functions.
    TIE2 Y897S Recombinant Human Active Protein Kinase
  • HY-E70797
    Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase
    CAMK2 is involved in the regulation of cellular processes in a variety of tissues. One member, CAMK2δ CAMK2D is involved in vasopressin signaling in the renal collecting duct, which controls water excretion through regulation of the water channel aquaporin-2 (AQP2). Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase is obtained by expressing CaMK2δ CAMK2D proteins and is biotinylated.
    Biotin-CaMK2δ CAMK2D Recombinant Human Active Protein Kinase
  • HY-E70810
    CaMK1β Recombinant Human Active Protein Kinase
    CaMK1 is present in several cell types and may be involved in various cellular processes. CaMK1 exists as different isoforms (α, β, γ and δ). CaMK1β Recombinant Human Active Protein Kinase is obtained by expressing CaMK1β proteins.
    CaMK1β Recombinant Human Active Protein Kinase
  • HY-E70811
    CaMK2α Recombinant Human Active Protein Kinase
    CAMK2 is involved in the regulation of cellular processes in a variety of tissues. CaMK2α Recombinant Human Active Protein Kinase is obtained by expressing CaMK2α proteins.
    CaMK2α Recombinant Human Active Protein Kinase
  • HY-E70812
    CaMK2β Recombinant Human Active Protein Kinase
    CAMK2 is involved in the regulation of cellular processes in a variety of tissues. CaMK2β Recombinant Human Active Protein Kinase is obtained by expressing CaMK2β proteins.
    CaMK2β Recombinant Human Active Protein Kinase
  • HY-E70854
    PKCε Recombinant Human Active Protein Kinase
    PKCε is an isoform of the large PKC family of protein kinases. In cardiac muscle cells, PKCε regulates muscle contraction through its actions at sarcomeric proteins, and PKCε modulates cardiac cell metabolism through its actions at mitochondria. PKCε Recombinant Human Active Protein Kinase is a recombinant PKCε protein that can be used to study PKCε-related functions.
    PKCε Recombinant Human Active Protein Kinase
  • HY-E71363
    papain (USP)
    Papain (USP) refers to Papain (HY-P1645) that meets the standards of the US Pharmacopoeia. Papain is a cysteine protease of the peptidase C1 family. Papain enhances red cell agglutination by anti-D and anti-A, and increases red cell sensitivity to K cell-mediated lysis in ADCC assays. Papain can induce pulmonary emphysema. Papain can be used for the researches of Rh haemolytic disease of the newborn and pulmonary emphysema.
    papain (USP)
  • HY-E71367
    Bromelain (USP)
    Bromelain USP is an orally active proteolytic agent. Bromelain USP converts plasminogen to plasmin to support fibrinolysis, cleaves CD44 adhesion molecules from cell surfaces, and diminishes uPAR expression and uPA activity. Bromelain USP can inhibit the activity of a variety of fungi and bacteria. Bromelain USP can be used for the research of angina pectoris, atherosclerotic disease, fungal infections, bacterial infections, chronic inflammatory bowel disease, and cancer.
    Bromelain (USP)
  • HY-I0400S
    N-Acetylneuraminic acid-13C 64162-77-2 98%
    N-Acetylneuraminic acid-13C is the 13C labeled N-Acetylneuraminic acid.
    N-Acetylneuraminic acid-13C
Cat. No. Product Name / Synonyms Application Reactivity